Ancestral splice variation is a key substrate for rapid diversification in African cichlids
Pooja and colleagues studied the gene expression patterns and patterns of alternative splicing of genes in all three radations of the East African Great Lakes and some non-radiating lineages. She finds that rapid changes in alternative splicing contributed more to early ecological divergence than shifts in gene expression levels.
Additionally, some new isoforms evolved remarkably fast, shaping diverse ecologies. This suggests that alternative splice variation, can be a powerful and labile source of rapid evolutionary innovation during early stages of adaptive radiation.